Upper And Lower Gastrointestinal Disorders Practice Exam Practice Tests

Question 1

A patient with GERD is prescribed omeprazole 40 mg daily. After 8 weeks, their symptoms are well-controlled. According to guidelines, what is the most appropriate next step?

Accepted Answer

Attempt to discontinue, step-down, taper, or use PRN dosing of the PPI.

Answer

Continue omeprazole 40 mg daily indefinitely.

Answer

Increase the dose of omeprazole to 80 mg daily.

Answer

Switch to a different PPI at the same dose.

Question 2

A patient presents with symptoms suggestive of PUD. Which of the following diagnostic tests is considered the MOST accurate for detecting *H. pylori* infection?

Accepted Answer

Endoscopic biopsy with histology

Answer

Serological testing

Answer

Urea breath test

Answer

Stool antigen test

Question 3

Which of the following medications are associated with an increased risk of GERD?

Answer

Antacids

Answer

NSAIDs

Answer

Calcium Channel Blockers (CCBs)

Answer

Benzodiazepines

Question 4

Triple therapy (PPI BID + clarithromycin 500 mg BID + amoxicillin 1000 mg BID x 14 days) is the preferred first-line treatment for *H. pylori* eradication in regions with high clarithromycin resistance.

Accepted Answer

True

Answer

False

Question 5

A patient with a history of NSAID use develops a gastric ulcer. What is the recommended duration of PPI therapy for ulcer healing, assuming *H. pylori* infection is ruled out?

Accepted Answer

8 weeks

Question 6

A patient is diagnosed with refractory GERD despite being on a twice-daily PPI. What is the next best step in management?

Accepted Answer

Further workup with EGD and consider additional agents like P-CABs.

Answer

Switch to an H2RA.

Answer

Increase the PPI dose to three times daily.

Answer

Add a prokinetic agent.

Question 7

A patient with a creatinine clearance (CrCl) of 40 mL/min is prescribed famotidine for GERD. What dosage adjustment is required?

Accepted Answer

Reduce the dose by 50%.

Answer

No dosage adjustment is required.

Answer

Increase the dose by 50%.

Answer

Discontinue famotidine and use a PPI instead.

Question 8

A patient with Crohn's disease is experiencing a flare-up. Their fecal calprotectin level is 800 $\mu$g/g. If the normal range is <50 $\mu$g/g, by what factor does their calprotectin level exceed the normal range?

Accepted Answer

16

Answer

4

Answer

8

Answer

32

Question 9

A patient with Ulcerative Colitis is prescribed mesalamine. If the patient takes 1.5 grams of mesalamine three times daily, what is the total daily dose in grams?

Accepted Answer

4.5

Question 10

A patient with IBS-D is prescribed loperamide 2mg after each loose stool, up to a maximum of 16mg per day. If the patient has 5 loose stools in a day, what is the total dose of loperamide they will take in mg?

Accepted Answer

10

Answer

2

Answer

5

Answer

16

Question 11

A patient with IBS-C is recommended to increase their soluble fiber intake by 5 grams per day. If they currently consume 2 grams of soluble fiber, they should aim for a total daily intake of 7 grams.

Accepted Answer

True

Answer

False

Question 12

Which of the following medications are commonly used to treat IBS-C?

Answer

PEG products

Answer

Rifaximin

Answer

Linaclotide

Answer

Lubiprostone

Question 13

A patient with Crohn's disease is prescribed infliximab. The initial dose is 5 mg/kg. If the patient weighs 70 kg, what is the initial dose in mg?

Accepted Answer

350

Answer

70

Answer

140

Answer

700

Question 14

A patient presents with acute cholangitis. Their bilirubin level is 5 mg/dL. If the normal range is 0.3-1.0 mg/dL, by what factor does their bilirubin exceed the upper limit of normal?

Accepted Answer

5

Answer

2

Answer

3

Answer

4

Question 15

A patient with diverticulitis is prescribed cefepime 2g IV q8h and metronidazole 500mg IV q6h. Calculate the total daily dose (in grams) of cefepime the patient will receive.

Accepted Answer

6

Question 16

A patient is prescribed ondansetron 8mg IV every 8 hours for nausea. The half-life of ondansetron is approximately 4 hours. Approximately how much of the initial dose remains in the patient's system after 12 hours, assuming first-order kinetics?

Accepted Answer

1 mg

Answer

4 mg

Answer

2 mg

Answer

0.5 mg

Question 17

A patient with acute pancreatitis has a serum lipase level that is two times the upper limit of normal. According to diagnostic criteria, this finding alone is sufficient to diagnose acute pancreatitis.

Accepted Answer

True

Answer

False

Question 18

Which of the following medications are classified as Class 1 medications associated with acute pancreatitis?

Answer

Didanosine

Answer

Azathioprine

Answer

ACE inhibitors

Answer

6-Mercaptopurine (6-MP)

Answer

SSRIs

Question 19

A patient with acute pancreatitis is receiving intravenous fluids at a rate of 1.5 mL/kg/hr. If the patient weighs 70 kg, what is the hourly fluid rate in mL?

Accepted Answer

105 mL/hr

Answer

70 mL/hr

Answer

90 mL/hr

Answer

120 mL/hr

Question 20

A patient with postoperative nausea and vomiting (PONV) is prescribed promethazine 12.5mg IV every 6 hours PRN. What is the maximum daily dose (in mg) of promethazine this patient can receive?

Accepted Answer

50

Upper And Lower Gastrointestinal Disorders Practice Exam Practice Tests

Practice Tests

Upper and Lower Gastrointestinal Disorders Practice Exam

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